/* RESET-MIN */
/*
Copyright (c) 2007, Yahoo! Inc. All rights reserved.
Code licensed under the BSD License:
http://developer.yahoo.net/yui/license.txt
version: 2.2.2
*/
body,div,dl,dt,dd,ul,ol,li,h1,h2,h3,h4,h5,h6,pre,form,fieldset,input,textarea,p,blockquote,th,td{margin:0;padding:0;}table{border-collapse:collapse;border-spacing:0;}fieldset,img{border:0;}address,caption,cite,code,dfn,em,strong,th,var{font-style:normal;font-weight:normal;}ol,ul {list-style:none;}caption,th {text-align:left;}h1,h2,h3,h4,h5,h6{font-size:100%;font-weight:normal;}q:before,q:after{content:'';}abbr,acronym {border:0;}
/* // RESET-MIN */


#sharethis_0 {
	display: none;
}

a {
	color: #369;
	text-decoration: none;
}
	a:hover {
		text-decoration: underline;
	}

	a img {
		border: none;
	}
	
	a.actionable {
		padding-left: 10px;
		font-weight: bold;
		background: url(/img/caret.gif) 0 3px no-repeat;
	}
	
p {
	line-height: 1.5em;
	margin: 0 0 1em 0;
}

strong {
	font-weight: bold;
}

em {
	font-style: italic;
}

blockquote {
	font-size: 14px;
	line-height: 1.42em;
	color: #517a91;
	margin: .5em 0 1em 0;
}

h1 {
	font-weight: bold;
	font-size: 18px;
	color: #333;
	line-height: 1.33em;
	margin-bottom: .5em;
}
	#column_right  h1 {
		font-size: 12px;
	}
	
h2 {
	font-weight: bold;
	font-size: 14px;
	color: #c00;
	line-height: 1.64em;
	text-transform: uppercase;
	margin-bottom: .33em;
}	
	
	.popup h2,
	body.page #column_right  h2,
	body.page #column_left  h2 {
		font-size: 11px;
		line-height: 1.25em;
		margin-bottom: .5em;
	}
		
	h2.clinical_trials,
	h2.pipeline {
		background-repeat: no-repeat;
		padding-left: 18px;
	}	
		h2.clinical_trials {
			background-image: url(/img/icon_trials.gif);		
		}
		h2.pipeline {
			background-image: url(/img/icon_pipeline.gif);
			background-position: 0 2px;	
		}

h3 {
	font-weight: bold;
	font-size: 1em;
	color: #666;
	margin: 0 0 1em 0;
}
		

hr {
	clear: both;
	height: 1px;
	background: url(/img/divider.gif) repeat-x;
	border: none;
	margin: 1em 0;
}


ol {
	margin-left: 15px;
	list-style-type: decimal;
	list-style-position: outside;
	background-image: none;
}
	ol li {
		background: none !important;
	}

input.text,
textarea,
input.button {
	border: 1px solid #ccc;
	color: #333;
	font: inherit;
}
	input.button {
		color: #369;
	}

	input.submit {
		background: transparent url(/img/btn_find.gif) 100% 50% no-repeat;
		padding: 0 12px 0 0;
		font-weight: bold;
		border: 0;
		color: #369;
	}


table {
	margin: 0 0 1em 0;
	border-collapse: collapse;
	width: 100%;
}
	table th {
		font-weight: bold;
		padding: 3px;
	}
	table td {
		padding: 6px 3px;
	}
	table tr {
		
	}
		table tr.odd {
			background: #f0f1e4;
		}


.content ul {
	margin: .5em 0 1em 0;
}
	.content li {
		margin: 0 0 1em 15px;
		padding: 0 0 0 9px;
		line-height: 1.5em;
		background: url(/img/bullet.gif) 0 7px no-repeat;
	}



.error, input.error, textarea.error, select.error {
	color: #c00 !important;
}

ul.errors {
	border: 1px solid #c00;
	padding: 20px !important;
	margin: 0 0 2em 0 !important;
	background: #ecc;
	color: #c00;
}

.clear {
	clear: both;
}
	br.clear {
		height: 1px;
	}

.bold {
	font-weight: bold;
}



.rss_link img {
	margin: 5em 0 1em 0;
}


form {
  display:inline;
}

	input {
		font: inherit;
		vertical-align: middle;
	}

	input.text, textarea {
		border: 1px solid #ccc;
		padding: 0 3px;
		color: #333;
	}
	
	textarea {
		height: 200px;
	}
	
	select {
		color: #333;
		border: 1px solid #ccc;		
	}

	select {
	  min-width:1.5em; /* firefox! */
	  font:normal 11px/1.33em helvetica, Geneva, sans-serif;
	}

	option {
	  font:normal 11px/1.33em helvetica, Geneva, sans-serif;
	}
	
	form .line {
		margin: 1em 0;
		clear: right;
	}
		form .line label {
			width: 125px;
			margin-right: 20px;
			float: left;
		}
		
			form .line label.long {
				width: auto;
			}
			
			form .line input.text,
			form .line textarea {
				width: 250px;
				padding: 1px 3px;
			}

			form .line input.error,
			form .line select.error,
			form .line textarea.error {
				border-color: #c00;
			}

/* WRAPPERS / STRUCTURAL */
body {
	text-align: center;
	background: #fff url(/img/bkgd.gif) 50% 0 repeat-y;
	font: normal normal normal 12px/1em Arial, sans-serif;
	color: #333;
}

.content, .block {
	position: static;
}

#content_wrapper {
	width: 974px;
	margin: 0 auto;
	padding: 0 0 25px 0;
	text-align: left;
}

#page_masthead {
	clear: both;
	padding-top: 1px;
	padding-bottom: 1px;
	border-bottom: 2px solid #2b566f;
}

	body.page #page_masthead {
		background: #fff url(/img/masthead_sec.jpg) 0 1px no-repeat;
		height: 93px;
	}
	
		body.section_press_room #page_masthead { background-image: url(/img/masthead_investors.jpg); }
		body.section_pipeline #page_masthead { background-image: url(/img/masthead_pipeline.jpg); }
		body.section_company #page_masthead { background-image: url(/img/masthead_company.jpg); }
		body.section_litx_therapy #page_masthead { background-image: url(/img/masthead_litx_therapy.jpg); }
		body.section_aptocine #page_masthead { background-image: url(/img/masthead_aptocine_therapy.jpg); }
		body.section_clinical_trials #page_masthead { background-image: url(/img/masthead_clinical_trials.jpg); }
		body.section_utility #page_masthead { background-image: url(/img/masthead_utility.jpg); }
	
		body.page #page_masthead h1 {
			color: #fff;
			margin: 35px 35px 0 35px;
			font-size: 24px;
			font-weight: normal;
			text-transform: uppercase;
			line-height: 1em;
		}

#content {
}
	body.homepage #content {
		margin-top: 12px;
		background: url(/img/divider_y.gif) 316px 0 repeat-y;
	}

	body.page #content {
		margin: 14px 0 2px 0;
		background: url(/img/divider_y.gif) 209px 0 repeat-y;
		*overflow: auto; /* stupid IE */
		_height: 1%; /* stupid IE 6 */
/*		min-height: 560px;*/
	}
		body.page #content .prop {
			width: 1px;
			height: 560px;
			float: left;
		}
	
		body.with_right_column #content {
			background-image: url(/img/divider_3col.gif) !important;
		}


#column_left {
	float: left;
}
	body.homepage #column_left {
		width: 290px;
		margin-left: 10px;
		padding: 0 0 25px 0;
	}
		
	body.page #column_left {
		width: 195px;
		margin: 0;
		font-size: 11px;
	}
	
		body.page #column_left .content {
			margin: 0 12px;
		}
		
		body.page #column_left .nav {
			margin: 0 0 30px 5px;
		}

#column_middle {

}
	body.homepage #column_middle {
		margin-left: 336px; /* 300px left col + 1px divider + 15px, 20px margins */
		padding: 0;
	}
	
	body.page #column_middle {
		margin: 0 10px 0 225px; /* 195px left col + 22px + 8px margins */
		width: 736px;
	}
		body.page #column_middle #middle_content_wrapper {
			float: left; /* this, to limit the scope of clearing elements within */
		}
	body.with_right_column #column_middle {
		width: 476px;
		margin-right: 266px;
	}
	
	

#column_right {
	float: right;
}
	body.page #column_right {
		width: 236px;
		margin: 0 2px 0 0;
		_margin: 0; /* stupid IE 6 */
		font-size: 11px;
	}
	
		body.page #column_right hr {
			border: 0;
			border-top: 6px solid #fff;
			height: 6px;
			background-color: #fff;
			background-image: none;
		}
		
		body.page #column_right .content {
			
		}
			body.page #column_right .block {
				/*padding: 18px 14px 18px 14px;*/
				margin: 18px 14px;
			}
			
			body.page #column_right img {
				margin-bottom: 11px;
			}

#footer {
	clear: both;
	margin-top: 1px;
	font-size: 10px;
	color: #666;
	text-align: right;
	padding: 17px 28px 18px 20px; /* height: 45px */
	background: #f0f1e4;
}

#copy {
	margin-right: 10px;
}


/* MASTHEAD */
#masthead {
	padding: 18px 15px 0 24px;	
	text-align: right;
	font-size: 11px;
	height: 75px;
}
	#masthead_content {}
		
		#nav_utility a {
			margin-left: 7px;
			border-left: 1px solid #ccc;
			padding-left: 8px;
		}
			#nav_utility a.first {
				margin: 0;
				padding: 0;
				border: 0;
			}

	#searchForm {
		background: url(/img/divider_toolbar.gif) no-repeat;
		display: inline;	
		margin-left: 7px;
		padding: 2px 0 2px 10px;
	}
		#searchForm input.text {
			width: 100px;
			font-size: 11px; /* stupid IE */
		}
		
		#searchForm #searchButton {
			padding: 0 10px 0 0;
			background: transparent;
			border: none;
			color: #517a91;
			font-size: 11px;
			font-weight: bold;
			text-transform: uppercase;
			background: url(/img/btn_find.gif) 100% 6px no-repeat;
			*background-position: 100% 4px; /* stupid IE */
		}

	#logo {
		float: left;
	}



#builtat {
	text-align: right;
	font-size: 9px;
	width: 954px;
	margin: 0 auto;
	padding: 0 0 45px 0;
}
	#builtat a {		
		color: #ccc;
	}


/* TOP-MENU */
#page_menu {
	background: url(/img/bkgd_nav.gif) repeat-x;
	height: 30px;
	padding-right: 70px;
	position: relative;
	z-index: 500;
}

ul#menu {
	font-size: 11px;
	text-transform: uppercase;
	line-height: 1em;
}
	ul#menu li {
		position: relative;
		float: right;
		border-left: 1px solid #fff;
		background: url(/img/bkgd_unav.gif) repeat-x;
	}
		ul#menu li.on,
		ul#menu li:hover {
			background: #668ba0 none;
		}
	
		ul#menu li.first {
			border-right: 1px solid #fff;
		}
		ul#menu li a {
			display: block;
			padding: 9px 14px 10px 25px;
			color: #fff;
			background: url(/img/caret_nav.gif) 14px 11px no-repeat;
		}
			ul#menu li a:hover,
			ul#menu li.on a {
				text-decoration: none;				
				background-image: url(/img/caret_nav_on.gif);
			}
	
	/*  SUBMENU */
	ul#menu ul.submenu {
		display: none;
		width: 195px;		
		position: absolute;
		top: 30px;
		left: -2px;
		
		background: #fff;
		
		border: 2px solid #335366;
		border-top: none;
	}
		ul#menu li:hover ul.submenu,
		ul#menu li.hover ul.submenu {
			display: block;
		}

		ul#menu ul.submenu li {
			float: none;
			background: transparent url(/img/divider.gif) 0 0 repeat-x;
			border: none;
			padding: 1px 0 0 0;
		}
			ul#menu ul.submenu li a {
				line-height: 1.25em;
				padding: 8px 14px 9px 25px;
				width: 156px;
				color: #369;
				background: url(/img/caret.gif) 14px 11px no-repeat;
			}
			ul#menu ul.submenu li a:hover {
				background-color: #668ba0;
				background-image: url(/img/caret_nav_on.gif);
				color: #fff;
			}

	ul#menu ul#submenu_investors {
		right: -2px;
		left: auto;
	}


/* SIDE NAV */
ul#nav {
	padding-top: 1px;
	font-size: 11px;
	font-weight: bold;
	text-transform: uppercase;
	background: url(/img/divider.gif) repeat-x;
}
	ul#nav li {
		background: url(/img/divider.gif) bottom left repeat-x;
	}
		ul#nav li a {
			display: block;
			padding: 8px 10px;	
			line-height: 1.25em;		
		}
			ul#nav li a:hover,
			ul#nav li.on a {
				text-decoration: none;
				color: #666;
			}

	ul#nav ul {
		background: none;
		margin: 0 0 0 15px;
	}
		ul#nav ul li {
			padding: 0;
			background: none;
			text-transform: none;
		}
			ul#nav ul li a {				
				background: url(/img/caret.gif) 0 7px no-repeat;
				padding: 5px 5px 5px 12px;
			}
				ul#nav li.on ul li a {
					color: #369;
				}
					ul#nav li.on ul li a.on,
					ul#nav li.on ul li a:hover {
						color: #666;
					}
				
				ul#nav ul li a:hover,
				ul#nav ul li.on a {
					background-image: url(/img/caret_nav_on.gif);
				}


/* VIDEO POPUPS */
.video_content {
	margin: 0 0 1em 0;
	position: relative;
}
	.video_content .popup {
		font-size: 11px;
		display: none;
		position: absolute;
		background: url(/img/border_video.gif) ;
		top: -100px;
		width: 744px;
		height: 382px;
		padding: 3px 0;		
	}
	
		.popup .actionable {
			text-transform: uppercase;
		}
	
		.video_content .popup .popup_content {
			background: #f0f1e4;
			padding: 15px 10px 15px 25px;
			height: 352px; /* 382px - padding */
			overflow: hidden;
		}
			.video_content .popup .popup_content img {
				margin: 0;
			}
			.video_content .popup_content .video {
				float: right;
			}
			.video_content .video_path {
				display: none;
			}
			.video_content .popup_content .description {
				margin: 0 15px 2em 0;
				height: 310px;
				overflow: auto;
			}

body.homepage #column_middle .video_content .popup {
	left: -106px;
	top: -255px;
}
	body.homepage #column_middle .video_content .popup .popup_content {
	}
	
body.page #column_right .video_content .popup {
	right: -16px;
	top: -100px;
}	


/* PIPELINE */
table.pipeline {
	border-collapse: separate;
	border-spacing: 1px 0;
	table-layout: fixed;
	empty-cells: show;
	width: 98%;
}
	table.pipeline th {
		color: #666;
		font-weight: bold;
		font-size: 11px;
		text-transform: uppercase;
		padding: 10px;
		text-align: center;
	}
	
	table.pipeline td {
		padding: 10px;
		font-weight: bold;
		text-align: center;
	}
	
		table.pipeline .indication {			
			text-align: left;
			width: 230px;
		}
	
	table.pipeline td.lit {
		/* inherit background color from tr.odd */
		background-image: url(/img/pipe_dot_white.gif);
		background-position: 50% 50%;
		background-repeat: no-repeat;
	}
	
		table.pipeline tr.odd td.lit {
			background-image: url(/img/pipe_dot.gif);
		}
	
	
	
	
	
/* SITEMAP */
#sitemap {
	
}
	#sitemap .col {
		width: 45%;
		float: left;
	}
	
	#sitemap .category {
		margin-bottom: 2em;
	}
	
		#sitemap .heading {
			font-weight: bold;
			text-transform: uppercase;
		}
	
	
/* PR */
.pr_nav {
	margin: 0 0 3em 0;
}

.pr_list_item {
	margin: 0 0 2em 0;
}


/* email addresses */
div.actionable {
	margin: 2em 0;
	line-height: 1.5em;	
	padding-left: 10px;
	font-weight: bold;
	background: url(/img/caret.gif) 0 .5em no-repeat;
}