Metastatic Colorectal Cancer (MCRC)
Metastatic colorectal cancer involves tumors primarily in the liver caused by metastases from primary colorectal cancer. The worldwide incidence of colorectal cancer is approximately one million cases per year (IARC 2002). The National Cancer Institute reports that approximately 50 percent of patients diagnosed with colorectal cancer will suffer from advanced disease that has metastasized to other parts of the body, most commonly to the liver (National Cancer Institute 2009). LSO has completed Aptocine treatment in a 483-patient Phase 3 trial for metastatic colorectal cancer in the liver, primarily at sites in Europe and India.
- International Agency for Research on Cancer. GLOBOCAN 2002. Available at: http://www-dep.iarc.fr/
- National Cancer Institute. Colon Cancer Treatment (PDQ): Stage IV and Recurrent Colon Cancer. 2009 Available at: http://www.cancer.gov/cancertopics/pdq/treatment/colon/HealthProfessional/page10