Metastatic Colorectal Cancer (MCRC)

Metastatic colorectal cancer involves tumors primarily in the liver caused by metastases from primary colorectal cancer. According to GLOBOCAN 2002, a cancer incidence database produced by the International Agency for Research on Cancer of the World Health Organization, the worldwide incidence of colorectal cancer is approximately one million cases per year. The National Cancer Institute reports that approximately 50 percent of patients diagnosed with colorectal cancer will suffer from advanced disease that has metastasized to other parts of the body, most commonly to the liver. Patient treatments using Litx in a Phase III trial for metastatic colorectal cancer began in June 2007, and involve approximately 450 patients, primarily at sites in Europe.