Pipeline

Current Clinical Trials

LSO has completed treatment in a Phase 3 trial in hepatocellular carcinoma and is currently enrolling patients in a Phase 3 trial in colorectal cancer metastatic to the liver, as well as a Phase 2 trial in benign prostatic hyperplasia (BPH).

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Indication Preclinical Phase 1 Phase 2 Phase 3
Hepatocellular Carcinoma        
Metastatic Colorectal Cancer        
Glioma        
Benign Prostatic Hyperplasia        
Age-related Macular Degeneration        
Peripheral Arterial Disease        
Coronary Artery Disease        
Cutaneous Vascular Malformations        

LSO is focusing on a number of cancers for the initial development of Aptocine™: Hepatoma, Metastatic Colorectal Cancer, Prostate Cancer, Pancreatic Cancer, Lung Cancer, Nasopharyngeal Cancer, Head and Neck Cancer, Kidney Cancer, and Glioma/Glioblastoma. Aptocine is also in Phase 2 development for treatment of Benign Prostatic Hyperplasia (BPH), and preclinical development for other non-cancer indications.